There are different views on what assets should be in the DeFi index. Depending on which assets are included in DeFi, the picture of price-performance may look completely different.

Synthetix led the DeFi race with a massive +3,117% gain with ChainLink  also performing well, earning +525.31% over the course of 2019.

I like the basket offered by @0x_Lucas, which includes equal weight of $ETH, $MKR, $SNX, $LINK, $ZRX, $KNC

2019 performance:

BTC: +86.44%
DeFi: +550.58%

2020 performance:

BTC: +28.9%
DeFi: +41.31% (top gainers are KNC +81.9%, LINK +58.4%)

DeFi Watchlist: https://cryptorank.io/watchlist/de02e9f496b4

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